Angiotensin Receptor Blockers
Angiotensin is a protein that regulates constriction of blood vessels. Excess of angiotensin causes many cardiovascular problem. More contraction (narrowing) of blood vessels increases blood pressure and increase work load on heart.Sudden drop of blood pressure may lead to stroke. Higher blood pressure damages blood vessels of entire body (including kidney). Damaged vessels may cause kidney malfunctions (medically known as Renal Failure) such as unable to remove wastes (harmfull chemicals and toxic) from blood and unwanted fluid from blood system. This may lead to further drop of blood pressure.
Angiotensin receptor blockers works by blocking action of angiotensin II. Angiotensin II receptors help relax blood vessels and, thereby, pressure exerted by blood on wall of vessels. It also increases width of vessels which stops further dilation.
Cough is one of prime side effects of ACE inhibiters. Angiotensin II receptors drug is prescribed as better alternative if pateint develops cough side effects. Like ACE inhibitors, angiotensin II receptors blockers are somewhat similar in action and different in producing side effects.
If you take an angiotensin II receptor blocker:
- You are less likely to have to go to hospital because of heart failure
- You are less likely to die of heart failure. The evidence for this is not as strong as it is for ACE inhibitors.
Side Effects of Angiotensin Receptor Blockers
- May affect kidney functioning
- Increases potassium level
- Low blood pressure (Most common)
- Diarrhea, muscle contraction or pain.
- Back or leg pain
- Sleeping problem. Can not fall asleep.
- Increase or descreas of heartbeat.
- Dizziness, lightheaded or faintness (These side effects may be severe if taken with diuretic drugs)
- Baffled or confused. Difficult in decision making.
- Dhydration caused by excess vomiting and diarrhea. Dehydration may futher lower blood pressure. Contact physician immedietly if this happens.
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